SCHEMBL28366972

SCHEMBL28366972

Oc1cccccc2ccccccc1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
HPGD P15428 3/20 1.00
HSD17B10 Q99714 3/20 1.00
BCL2L1 Q07817 1/20 1.00
BACE1 P56817 1/20 0.65
ALOX5 P09917 1/20 0.61
L3MBTL1 Q9Y468 2/20 0.54
BRD4 O60885 1/20 0.53
NR1I2 O75469 1/20 0.53
SMARCA2 P51531 1/20 0.53
SMARCA4 P51532 1/20 0.53
PBRM1 Q86U86 1/20 0.53
HDAC4 P56524 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.50
ALOX15 P16050 3/20 0.50
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylphenol SCHEMBL14249267 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10BCL2L1BACE1
2-Phenylphenol SCHEMBL29360750 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10BCL2L1BACE1
2-Phenylphenol SCHEMBL27831345 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10BCL2L1BACE1
2-Phenylphenol SCHEMBL29811 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10BCL2L1BACE1
2-Phenylphenol SCHEMBL8154843 0.97 ALDH1A1 (0.94) ALDH1A1HPGDHSD17B10BCL2L1BACE1
2-Phenylphenol SCHEMBL2808236 0.97 ALDH1A1 (0.94) ALDH1A1HPGDHSD17B10BCL2L1BACE1
2-Phenylphenol SCHEMBL4583229 0.97 ALDH1A1 (0.94) ALDH1A1HPGDHSD17B10BCL2L1BACE1
2-Phenylphenol SCHEMBL6281141 0.97 ALDH1A1 (0.94) ALDH1A1HPGDHSD17B10BCL2L1BACE1
2-Phenylphenol SCHEMBL7622365 0.97 ALDH1A1 (0.94) ALDH1A1HPGDHSD17B10BCL2L1BACE1
2-Phenylphenol SCHEMBL3038135 0.97 HPGD (0.94) ALDH1A1HPGDHSD17B10BCL2L1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107987189-B Catalyst component for olefin polymerization and preparation method and application thereof 中国石油化工股份有限公司 2021-05-11 CN claimed
CN-107987189-B Catalyst component for olefin polymerization and preparation method and application thereof 中国石油化工股份有限公司 2021-05-11 CN disclosed
CN-110869348-A Pyrrole compound, perfume composition, and food, drink and cosmetic containing same 长谷川香料株式会社 2020-03-06 CN disclosed