Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27165159 | 0.85 | TRPV1 (0.55) | NPC1RAB9ATRPV1FAAHPKM | |
| SCHEMBL471106 | 0.83 | LMNA (0.57) | NPC1RAB9ATRPV1FAAHMAPT | |
| SCHEMBL26758486 | 0.83 | NPC1 (0.56) | NPC1RAB9ATP53SMN1; SMN2HSD11B1 | |
| SCHEMBL22581792 | 0.83 | DEGS1 (0.67) | NPC1RAB9ATP53SMN1; SMN2HSD11B1 | |
| SCHEMBL3258353 | 0.81 | TRPV1 (0.60) | NPC1RAB9ASMN1; SMN2TRPV1FAAH | |
| SCHEMBL16585513 | 0.80 | TRPV1 (0.59) | NPC1RAB9ATP53SMN1; SMN2TRPV1 | |
| SCHEMBL1172000 | 0.80 | NPC1 (0.83) | NPC1RAB9ATP53SMN1; SMN2HSD11B1 | |
| SCHEMBL2475564 | 0.79 | FNTA (0.46) | NPC1RAB9ASMN1; SMN2TRPV1FAAH | |
| SCHEMBL9378280 | 0.79 | TRPV1 (0.57) | NPC1RAB9ASMN1; SMN2TRPV1FAAH | |
| SCHEMBL17187727 | 0.77 | CYP2C9 (0.60) | NPC1RAB9ASMN1; SMN2TRPV1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110878070-B | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2021-08-31 | — | — | CN | disclosed |
| CN-110878070-A | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2020-03-13 | — | — | CN | disclosed |