SCHEMBL28367333

SCHEMBL28367333

CC(O)c1nccn1C.Cc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.50

Known targets — ChEMBL curated mechanism

ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
KDM4E B2RXH2 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
LMNA P02545 2/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP2D6 P10635 5/20 0.39
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 2/20 0.37
MEN1 O00255 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
CASP1 P29466 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPK1 P28482 1/20 0.36
GAA P10253 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL27778946 0.83 KDM4E (0.49) TSHRKDM4EL3MBTL1ALDH1A1MAPT
Sulfuric Acid SCHEMBL17273283 0.83 KDM4E (0.49) TSHRKDM4EL3MBTL1ALDH1A1MAPT
SCHEMBL27774303 0.82 KDM4E (0.47) TSHRKDM4EL3MBTL1ALDH1A1MAPT
SCHEMBL28487074 0.82 TSHR (0.44) TSHRKDM4EL3MBTL1ALDH1A1MAPT
SCHEMBL2998201 0.81 KDM4E (0.51) TSHRKDM4EL3MBTL1ALDH1A1MAPT
SCHEMBL28831790 0.80 TSHR (0.42) TSHRKDM4EL3MBTL1ALDH1A1MAPT
SCHEMBL31037659 0.80 TSHR (0.40) TSHRKDM4EL3MBTL1ALDH1A1MAPT
Toluene SCHEMBL28782370 0.79 KDM4E (0.61) KDM4EL3MBTL1MAPTCYP2D6MEN1
SCHEMBL23863190 0.78
SCHEMBL27774294 0.78 KDM4E (0.44) TSHRKDM4EL3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118957588-B Metal film wiring etching solution and preparation method and application thereof 达高工业技术研究院(广州)有限公司 2025-03-11 CN claimed
CN-119552136-A Preparation method of 5-hydroxymethylfurfural aqueous solution 中国科学院大连化学物理研究所 2025-03-04 CN claimed
CN-119219233-A Nitrate removal method for salt-separating mother liquor of chemical high-salt wastewater 北京恒其德生科技有限公司 2024-12-31 CN claimed
CN-118957588-A Metal film wiring etching solution and preparation method and application thereof 达高工业技术研究院(广州)有限公司 2024-11-15 CN claimed
CN-118817778-A Humidity sensing material and preparation method and application thereof 中移园区建设发展有限公司 2024-10-22 CN claimed
CN-118222086-B Precipitation-resistant halogen-free flame-retardant polyamide composition and preparation method thereof 诺为新材料(杭州)有限责任公司 2024-10-18 CN claimed
CN-118222086-A Precipitation-resistant halogen-free flame-retardant polyamide composition and preparation method thereof 诺为新材料(杭州)有限责任公司 2024-06-21 CN claimed
CN-118126000-A Preparation method of 5-hydroxymethylfurfural 中国科学院大连化学物理研究所 2024-06-04 CN claimed
CN-118026970-A Preparation method of 5-hydroxymethylfurfural 中国科学院大连化学物理研究所 2024-05-14 CN claimed
CN-118026971-A Preparation method of 5-hydroxymethylfurfural 中国科学院大连化学物理研究所 2024-05-14 CN claimed
CN-118005580-A Preparation method of 5-hydroxymethylfurfural 中国科学院大连化学物理研究所 2024-05-10 CN claimed
CN-117986211-A Preparation method of 5-hydroxymethylfurfural 中国科学院大连化学物理研究所 2024-05-07 CN claimed
CN-117986210-A Preparation method of 5-hydroxymethylfurfural 中国科学院大连化学物理研究所 2024-05-07 CN claimed
CN-117270341-A Chip photoresist stripper composition, and preparation method and application thereof 浙江奥首材料科技有限公司 2023-12-22 CN claimed
CN-111435705-B Repairing agent and repairing method thereof and method for preparing photoelectric film 杭州纤纳光电科技有限公司 2023-04-07 CN claimed
CN-114824206-A Long-life high-first-efficiency hard carbon composite material and preparation method thereof 晖阳(贵州)新能源材料有限公司 2022-07-29 CN claimed
CN-114570219-A Pollution-resistant separation membrane with ionic liquid layer on surface and preparation method thereof 浙江大学 2022-06-03 CN claimed
CN-112086564-A Passivating agent and passivation method thereof and method for preparing semiconductor film 杭州纤纳光电科技有限公司 2020-12-15 CN claimed
CN-108556186-B Comprehensive treatment method of polyurethane waste material 佛山市罟特化工贸易有限公司 2020-09-29 CN claimed
CN-111435705-A Repairing agent and repairing method thereof and method for preparing photoelectric film 杭州纤纳光电科技有限公司 2020-07-21 CN claimed