SCHEMBL28367704

SCHEMBL28367704

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(OP(=O)(O)OP(=O)(O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 7/20 0.84
P2RY2 P41231 4/20 0.84
P2RX1 P51575 4/20 0.84
P2RX3 P56373 4/20 0.84
SRC P12931 2/20 0.84
SMN1; SMN2 Q16637 2/20 0.84
P2RX2 Q9UBL9 2/20 0.84
ALDH1A1 P00352 2/20 0.84
P2RX4 Q99571 1/20 0.84
TRPM2 O94759 2/20 0.80
TAS1R3 Q7RTX0 2/20 0.80
TAS1R1 Q7RTX1 2/20 0.80
DNPH1 O43598 1/20 0.80
PRKAB2 O43741 1/20 0.80
LDHA P00338 1/20 0.80
ADRB2 P07550 1/20 0.80
FBP1 P09467 1/20 0.80
ADORA1 P30542 1/20 0.80
PRKAG1 P54619 1/20 0.80
PRKAA2 P54646 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28646263 1.00 P2RY1 (0.84) P2RY1P2RY2P2RX1P2RX3SRC
SCHEMBL6242721 1.00 P2RY1 (0.84) P2RY1P2RY2P2RX1P2RX3SRC
SCHEMBL29001533 0.99 P2RY1 (0.82) P2RY1P2RY2P2RX1P2RX3SRC
SCHEMBL28755762 0.99 P2RY1 (0.82) P2RY1P2RY2P2RX1P2RX3SRC
SCHEMBL28397749 0.98 P2RY1 (0.84) P2RY1P2RY2P2RX1P2RX3SRC
SCHEMBL459771 0.98 P2RY1 (0.84) P2RY1P2RY2P2RX1P2RX3SRC
SCHEMBL459997 0.98 P2RY1 (0.84) P2RY1P2RY2P2RX1P2RX3SRC
SCHEMBL2321068 0.98 P2RY1 (0.81) P2RY1P2RY2P2RX1P2RX3SRC
SCHEMBL1746647 0.98 P2RY1 (0.84) P2RY1P2RY2P2RX1P2RX3SRC
SCHEMBL28210249 0.98 P2RY1 (0.81) P2RY1P2RY2P2RX1P2RX3SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115777017-A Compositions and methods for T cell engineering 亘喜生物科技(上海)有限公司 2023-03-10 CN disclosed
CN-115768880-A Compositions and methods for T cell engineering 亘喜生物科技(上海)有限公司 2023-03-07 CN disclosed
CN-115298200-A Genetically modified plants and methods of making the same 恩派瑞安神经科学公司 2022-11-04 CN disclosed
CN-115003701-A Receptor for enhancing immune cell function 北京卡替医疗技术有限公司 2022-09-02 CN disclosed
CN-114981409-A Methods and compositions for genomic integration 美洛德生物医药公司 2022-08-30 CN disclosed
CN-114981415-A Systems and methods for enhanced immunotherapy 杭州启函生物科技有限公司 2022-08-30 CN disclosed
CN-114829381-A Genetically modified plants and methods for making the same 恩派瑞安神经科学公司 2022-07-29 CN disclosed
CN-114787363-A Genetic engineering of fungi to modulate tryptamine expression 恩派瑞安神经科学公司 2022-07-22 CN disclosed
CN-113811602-A Adjuvant capable of boosting immune cells to expand in vivo 北京卡替医疗技术有限公司 2021-12-17 CN disclosed
CN-111292804-B Method and system for detecting SMN1 gene mutation by means of high-throughput sequencing 北京智因东方诊断科技有限公司 2021-11-26 CN disclosed
CN-113574172-A Compositions and methods for immunotherapy 亘喜生物科技(上海)有限公司 2021-10-29 CN disclosed
CN-113383071-A Compositions and methods for T cell engineering 亘喜生物科技(上海)有限公司 2021-09-10 CN disclosed
CN-112888794-A Compositions, methods and systems for processing or analyzing a multi-species nucleic acid sample 潘森纳丽斯股份有限公司 2021-06-01 CN disclosed
CN-111676195-A UCAR immune cell for treating T cell tumor 北京卡替医疗技术有限公司 2020-09-18 CN disclosed
CN-111544585-A Adjuvant capable of boosting immune cells to expand in vivo 北京卡替医疗技术有限公司 2020-08-18 CN disclosed
CN-111542595-A Modified immune cells and uses thereof 北京卡替医疗技术有限公司 2020-08-14 CN disclosed
CN-111292804-A Method and system for detecting SMN1 gene mutation by means of high-throughput sequencing 北京智因东方转化医学研究中心有限公司 2020-06-16 CN disclosed
CN-110832074-A Application of CRISPR-Cas endonuclease in plant genome engineering 科沃施种子欧洲股份两合公司 2020-02-21 CN disclosed
CN-110747186-A CRISPR/Cas9 systems and methods for efficient generation of mutants not carrying a transgenic element in plants 北京大学 2020-02-04 CN disclosed