Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31246329 | 0.79 | LMNA (0.43) | LMNAHSD17B10CA1CA2TSHR | |
| SCHEMBL8621947 | 0.78 | LMNA (0.30) | LMNAALOX15BLMPMP22MAPT | |
| SCHEMBL27818057 | 0.77 | TDP1 (0.33) | TSHRTDP1 | |
| SCHEMBL8669517 | 0.76 | LMNA (0.31) | LMNAHSD17B10ALOX15 | |
| SCHEMBL16300071 | 0.76 | LMNA (0.35) | LMNAHSD17B10ALOX15 | |
| SCHEMBL10437649 | 0.76 | KDM4E (0.31) | LMNAHSD17B10ALOX15TDP1BLM | |
| SCHEMBL6799805 | 0.76 | LMNA (0.31) | LMNAHSD17B10ALOX15TSHR | |
| SCHEMBL887079 | 0.75 | TDP1 (0.36) | TDP1 | |
| SCHEMBL4152740 | 0.75 | LMNA (0.43) | LMNAALOX15TSHRTDP1BLM | |
| SCHEMBL6937150 | 0.74 | TSHR (0.40) | TSHRTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496299-A | PSMA targeted radioactive diagnosis and treatment integrated medicine and synthesis and application thereof | 无锡诺宇医药科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-118496305-A | PSMA targeted radiopharmaceuticals, synthesis and uses thereof | 无锡诺宇医药科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-110809467-B | Modulators of SESTRIN-GATOR2 interactions and uses thereof | 纳维托制药有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-110809467-A | Modulators of SESTRIN-GATOR2 interaction and uses thereof | 纳维托制药有限公司 | 2020-02-18 | — | — | CN | disclosed |