Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28369182 | 0.84 | TAAR1 (0.44) | TAAR1SLC1A1MPOPPARGPPARA | |
| SCHEMBL29181170 | 0.83 | TAAR1 (0.53) | TAAR1SLC1A1PPARGPPARAADRB1 | |
| SCHEMBL25046506 | 0.83 | TAAR1 (0.53) | TAAR1SLC1A1PPARGPPARAADRB1 | |
| SCHEMBL30801383 | 0.83 | TAAR1 (0.53) | TAAR1SLC1A1PPARGPPARAADRB1 | |
| SCHEMBL28368827 | 0.81 | MPO (0.44) | TAAR1SLC1A1MPOADRB2ADRB1 | |
| SCHEMBL3122648 | 0.81 | ANPEP (0.46) | TAAR1SLC1A1ANPEPPPARGPPARA | |
| SCHEMBL7115349 | 0.80 | ANPEP (0.48) | TAAR1ANPEPMEN1KMT2A | |
| SCHEMBL10586409 | 0.79 | SLC1A1 (0.49) | TAAR1SLC1A1PPARGPPARAMEN1 | |
| SCHEMBL15178111 | 0.79 | SLC1A1 (0.49) | TAAR1SLC1A1PPARGPPARAMEN1 | |
| SCHEMBL4426896 | 0.77 | SLC1A1 (0.50) | TAAR1SLC1A1PPARGPPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764904-B | Aza-pyridone compounds and uses thereof | 詹森生物制药有限公司 | 2020-02-11 | — | — | CN | disclosed |