Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747899 | 0.65 | KDM4A (0.37) | GDAPDPK1KDM4EMAPT | |
| SCHEMBL19730160 | 0.65 | PNP (0.44) | GDAPDPK1KDM4EALDH1A1MAPT | |
| SCHEMBL5158005 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL3353320 | 0.64 | KDM4A (0.36) | GDAPDPK1KDM4EMAPT | |
| SCHEMBL3428780 | 0.61 | IDO1 (0.46) | GDA | |
| Hydrochloric Acid SCHEMBL30321313 | 0.60 | IDO1 (0.44) | GDA | |
| SCHEMBL19420514 | 0.60 | — | — | |
| SCHEMBL19409226 | 0.60 | — | — | |
| SCHEMBL5173516 | 0.59 | — | — | |
| SCHEMBL3170605 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827893-B | Preparation method of 4-chloro-7H-pyrrolo [2,3-d ] pyrimidine | 常州齐晖药业有限公司 | 2020-03-27 | — | — | CN | disclosed |