Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 16/20 | 0.67 |
| ▸ | AR | P10275 | 3/20 | 0.60 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28369978 | 0.86 | MAPK8 (0.67) | MAPK8ARMAPK9MAPK10 | |
| SCHEMBL28369917 | 0.85 | MAPK8 (0.65) | MAPK8ARMAPK9MAPK10 | |
| SCHEMBL4713332 | 0.80 | MAPK8 (1.00) | MAPK8MAPK9MAPK10 | |
| SCHEMBL28365579 | 0.78 | MAPK8 (0.60) | MAPK8ARMAPK9MAPK10 | |
| SCHEMBL2886834 | 0.77 | MAPK8 (0.49) | MAPK8AR | |
| SCHEMBL182807 | 0.76 | MAPK8 (0.57) | MAPK8AR | |
| SCHEMBL4711224 | 0.74 | MAPK8 (1.00) | MAPK8MAPK9MAPK10 | |
| SCHEMBL4709740 | 0.74 | MAPK8 (0.90) | MAPK8MAPK9MAPK10 | |
| SCHEMBL2991427 | 0.74 | KDM4E (0.59) | MAPK8AR | |
| SCHEMBL28370091 | 0.74 | MAPK8 (0.55) | MAPK8ARMAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746335-B | Polysubstituted pyrrole compound and synthesis method thereof | 南京师范大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-110746335-A | Polysubstituted pyrrole compound and synthesis method thereof | 南京师范大学 | 2020-02-04 | — | — | CN | disclosed |