Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 13/20 | 0.63 |
| ▸ | ABL1 | P00519 | 7/20 | 0.63 |
| ▸ | BCR | P11274 | 4/20 | 0.63 |
| ▸ | SRC | P12931 | 4/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.63 |
| ▸ | EGFR | P00533 | 2/20 | 0.63 |
| ▸ | FYN | P06241 | 2/20 | 0.63 |
| ▸ | YES1 | P07947 | 2/20 | 0.63 |
| ▸ | LYN | P07948 | 2/20 | 0.63 |
| ▸ | HCK | P08631 | 2/20 | 0.63 |
| ▸ | KIT | P10721 | 2/20 | 0.63 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.63 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.63 |
| ▸ | FGR | P09769 | 1/20 | 0.63 |
| ▸ | JAK3 | P52333 | 1/20 | 0.63 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.63 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.63 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | SIK1 | P57059 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20785959 | 0.92 | PKMYT1 (0.66) | LCKABL1BCRSRCMAPK14 | |
| SCHEMBL774847 | 0.89 | LCK (0.71) | LCKABL1BCRSRCMAPK14 | |
| SCHEMBL20633284 | 0.88 | LCK (0.76) | LCKABL1BCRSRCMAPK14 | |
| SCHEMBL4462679 | 0.88 | LCK (0.64) | LCKABL1BCRSRCMAPK14 | |
| SCHEMBL21875005 | 0.88 | ABL1 (0.64) | LCKABL1BCRSRCMAPK14 | |
| SCHEMBL22964561 | 0.87 | LCK (0.60) | LCKABL1BCRSRCMAPK14 | |
| SCHEMBL21875019 | 0.86 | ABL1 (0.64) | LCKABL1BCRSRCMAPK14 | |
| SCHEMBL1146860 | 0.86 | LCK (0.85) | LCKABL1BCRSRCMAPK14 | |
| SCHEMBL29355730 | 0.86 | LCK (0.85) | LCKABL1BCRSRCMAPK14 | |
| SCHEMBL30152032 | 0.86 | ABL1 (0.64) | LCKABL1BCRSRCMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107043375-B | Novel method for preparing dasatinib and intermediate thereof | 江苏食品药品职业技术学院 | 2020-03-20 | — | — | CN | disclosed |