Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367944 | 0.86 | MAOB (0.58) | MAOBKDM4EAHRAKR1B1MAPK1 | |
| SCHEMBL28368123 | 0.85 | MAOB (0.57) | MAOBKDM4EAHRAKR1B1ALOX5 | |
| SCHEMBL16693136 | 0.82 | MAOB (0.53) | MAOBKDM4EAHRAKR1B1ALOX5 | |
| SCHEMBL28367841 | 0.82 | MAOB (0.54) | MAOBKDM4EAKR1B1ALOX5MAPK1 | |
| SCHEMBL20065157 | 0.80 | MAOB (0.54) | MAOBKDM4EAHRAKR1B1ALOX5 | |
| SCHEMBL19744202 | 0.79 | AKR1B1 (0.58) | MAOBKDM4EAHRAKR1B1MAPK1 | |
| SCHEMBL31215466 | 0.78 | MAOB (0.55) | MAOBKDM4EAHRAKR1B1ALOX5 | |
| SCHEMBL8150841 | 0.77 | KDM4E (0.56) | MAOBKDM4EAHRAKR1B1ALDH1A1 | |
| SCHEMBL2493208 | 0.77 | KDM4E (0.67) | MAOBKDM4EAHRALDH1A1HPGD | |
| SCHEMBL8251037 | 0.77 | MAOB (0.72) | MAOBAKR1B1MAPK1SLC2A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770233-B | Fused bicyclic compound and application thereof in medicine | 广东东阳光药业有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-110770233-A | Fused bicyclic compound and application thereof in medicine | 广东东阳光药业有限公司 | 2020-02-07 | — | — | CN | disclosed |