Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301709 | 0.81 | RAPGEF4 (0.43) | RAPGEF4 | |
| SCHEMBL15077511 | 0.79 | RAPGEF4 (0.43) | RAPGEF4 | |
| SCHEMBL16862694 | 0.79 | RAPGEF4 (0.32) | RAPGEF4 | |
| Silver SCHEMBL31010581 | 0.78 | RAPGEF4 (0.41) | RAPGEF4 | |
| SCHEMBL31325570 | 0.78 | RAPGEF4 (0.41) | RAPGEF4 | |
| SCHEMBL8773546 | 0.78 | RAPGEF4 (0.41) | RAPGEF4 | |
| Bromide SCHEMBL3679642 | 0.78 | RAPGEF4 (0.41) | RAPGEF4 | |
| Iodide SCHEMBL9662368 | 0.78 | RAPGEF4 (0.41) | RAPGEF4 | |
| SCHEMBL15825735 | 0.76 | RAPGEF4 (0.34) | RAPGEF4 | |
| SCHEMBL8268053 | 0.71 | RAPGEF4 (0.52) | RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813596-A | Macrocyclic HCV NS3 inhibits tripeptide synthesis | 吉利德科学公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-111320610-B | Macrocyclic HCV NS3 inhibits tripeptide synthesis | 吉利德科学公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-111320610-A | Macrocyclic HCV NS3 inhibits the synthesis of tripeptides | 吉利德制药有限责任公司 | 2020-06-23 | — | — | CN | disclosed |
| CN-105849118-B | Macrocyclic HCV NS3 inhibits the synthesis of tripeptides | 吉利德制药有限责任公司 | 2020-03-31 | — | — | CN | disclosed |