Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | RARA | P10276 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | THRA | P10827 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 4/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.53 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | PLK1 | P53350 | 3/20 | 0.52 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373608 | 1.00 | RARB (0.65) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL28373605 | 0.89 | NPC1 (0.54) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL12491077 | 0.84 | THRA (0.69) | THRATHRBS1PR1SPHK1 | |
| SCHEMBL15329730 | 0.84 | THRA (0.69) | THRATHRBS1PR1SPHK1 | |
| SCHEMBL503506 | 0.84 | RARB (0.90) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL18979307 | 0.84 | RARB (0.90) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL2185929 | 0.84 | RARB (0.90) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL503648 | 0.84 | RARB (0.90) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL270423 | 0.84 | RARB (0.90) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL1164529 | 0.84 | RARB (0.90) | RARBMEN1ALDH1A1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110963935-A | 1-phenyl-2-aminoacetophenone derivative and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-04-07 | — | — | CN | claimed |
| CN-110963935-A | 1-phenyl-2-aminoacetophenone derivative and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-04-07 | — | — | CN | disclosed |