Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.33 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82158 | 0.91 | CYP1A1 (0.39) | POLBCYP1A1CYP1A2CYP1B1CYP3A4 | |
| SCHEMBL29475061 | 0.91 | CYP1A1 (0.39) | POLBCYP1A1CYP1A2CYP1B1CYP3A4 | |
| SCHEMBL82157 | 0.91 | CYP1A1 (0.39) | POLBCYP1A1CYP1A2CYP1B1CYP3A4 | |
| SCHEMBL86657 | 0.91 | CYP1A1 (0.39) | POLBCYP1A1CYP1A2CYP1B1CYP3A4 | |
| SCHEMBL82967 | 0.88 | CYP1A1 (0.35) | POLBCYP1A1CYP1A2CYP1B1CYP3A4 | |
| SCHEMBL29475036 | 0.88 | CYP1A1 (0.35) | POLBCYP1A1CYP1A2CYP1B1CYP3A4 | |
| SCHEMBL82968 | 0.88 | CYP1A1 (0.35) | POLBCYP1A1CYP1A2CYP1B1CYP3A4 | |
| SCHEMBL15119595 | 0.88 | TBXAS1 (0.33) | POLBCYP1A1CYP1A2CYP1B1CYP3A4 | |
| SCHEMBL86825 | 0.88 | KMT2A (0.36) | POLBTDP1ALDH1A1GPR6PIK3CB | |
| SCHEMBL86675 | 0.87 | KMT2A (0.33) | POLBCYP1A1CYP1A2CYP1B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109729716-B | PI3K inhibitor combination | 拜耳制药股份公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-105934256-B | PI3K inhibitor combination | 拜耳制药股份公司 | 2019-12-27 | — | — | CN | disclosed |