Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.81 |
| ▸ | BAG3 | O95817 | 1/20 | 0.71 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.69 |
| ▸ | ITGAM | P11215 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.66 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.66 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783127 | 1.00 | PPARG (0.81) | PPARGBAG3ITGB2ITGAMMEN1 | |
| SCHEMBL21783145 | 0.90 | PPARG (1.00) | PPARGBAG3ITGB2ITGAMMEN1 | |
| SCHEMBL20534466 | 0.89 | MEN1 (0.81) | PPARGBAG3ITGB2ITGAMMEN1 | |
| SCHEMBL20534465 | 0.89 | MEN1 (0.81) | PPARGBAG3ITGB2ITGAMMEN1 | |
| SCHEMBL21783153 | 0.89 | PPARG (0.84) | PPARGBAG3MEN1KMT2APOLB | |
| SCHEMBL9013025 | 0.88 | AKR1B1 (0.79) | PPARGMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9013028 | 0.88 | AKR1B1 (0.79) | PPARGMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL21783142 | 0.88 | PPARG (0.82) | PPARGBAG3ITGB2ITGAMMEN1 | |
| SCHEMBL21783164 | 0.88 | PPARG (1.00) | PPARGBAG3ITGB2ITGAMMEN1 | |
| SCHEMBL21783171 | 0.88 | PPARG (0.82) | PPARGBAG3ITGB2ITGAMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621315-A | Heterocyclic inhibitors of lysine biosynthesis via the diaminopimelic acid pathway | 拉筹伯大学 | 2019-12-27 | — | — | CN | disclosed |