Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 9/20 | 0.79 |
| ▸ | PPARG | P37231 | 4/20 | 0.79 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.60 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013028 | 1.00 | AKR1B1 (0.79) | AKR1B1PPARGCA9MAPTKDM4E | |
| SCHEMBL21783127 | 0.88 | PPARG (0.81) | AKR1B1PPARGMAPTPOLBMEN1 | |
| SCHEMBL28374629 | 0.88 | PPARG (0.81) | AKR1B1PPARGMAPTPOLBMEN1 | |
| SCHEMBL9011343 | 0.85 | AKR1B1 (0.84) | AKR1B1CA9MAPT | |
| SCHEMBL9011346 | 0.85 | AKR1B1 (0.84) | AKR1B1CA9MAPT | |
| SCHEMBL20659792 | 0.82 | AKR1B1 (0.60) | AKR1B1PPARGCA9MAPTPOLB | |
| SCHEMBL14527005 | 0.79 | ALDH1A1 (0.67) | AKR1B1CA9MAPTKDM4EMEN1 | |
| SCHEMBL14907050 | 0.79 | MAPT (0.62) | AKR1B1PPARGMAPTKDM4EPOLB | |
| SCHEMBL16034549 | 0.79 | MAPT (0.62) | AKR1B1PPARGMAPTKDM4EPOLB | |
| SCHEMBL21783145 | 0.78 | PPARG (1.00) | AKR1B1PPARGMAPTPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8109175-A | — | — | None | — | — | JP | disclosed |
| JP-H08109175-A | THIAZOLIDIN-2-ONE ESTER DERIVATIVE | TORII YAKUHIN KK | 1996-04-30 | — | — | JP | disclosed |