Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 12/20 | 1.00 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PDE6D | O43924 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28375287 | 0.90 | PIN1 (0.83) | PIN1DRD2DRD3MAPTTP53 | |
| SCHEMBL28372577 | 0.89 | PIN1 (1.00) | PIN1DRD2DRD3TP53SMN1; SMN2 | |
| SCHEMBL28375290 | 0.88 | PIN1 (0.83) | PIN1DRD2DRD3MAPTTP53 | |
| SCHEMBL28371162 | 0.87 | PIN1 (0.81) | PIN1DRD2DRD3TP53LMNA | |
| SCHEMBL28377315 | 0.85 | PIN1 (1.00) | PIN1LMNAPDE6D | |
| SCHEMBL28376525 | 0.83 | PIN1 (1.00) | PIN1DRD2DRD3PTGER4 | |
| SCHEMBL10738559 | 0.81 | PIN1 (0.67) | PIN1DRD2DRD3TP53SMN1; SMN2 | |
| SCHEMBL28591326 | 0.78 | PIN1 (0.64) | PIN1DRD2TP53SMN1; SMN2LMNA | |
| SCHEMBL28377322 | 0.76 | PIN1 (0.65) | PIN1DRD2DRD3MAPTTP53 | |
| SCHEMBL20715562 | 0.76 | PIN1 (0.67) | PIN1DRD2DRD3MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905241-B | 1, 2-disubstituted benzimidazole derivative and application thereof | 沈阳药科大学 | 2020-03-17 | — | — | CN | claimed |
| CN-106905241-B | 1, 2-disubstituted benzimidazole derivative and application thereof | 沈阳药科大学 | 2020-03-17 | — | — | CN | disclosed |