Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472473 | 0.85 | CYP2C19 (0.41) | LMNACYP3A4TSHRABCB11CYP1A2 | |
| SCHEMBL15325061 | 0.78 | MAPK1 (0.36) | KDM4ELMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL7392441 | 0.78 | MAPK1 (0.36) | KDM4ELMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL7392443 | 0.78 | MAPK1 (0.36) | KDM4ELMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL7392445 | 0.78 | MAPK1 (0.36) | KDM4ELMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL2357465 | 0.77 | KDM4E (0.40) | KDM4ELMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10389179 | 0.77 | KDM4E (0.40) | KDM4ELMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL28662943 | 0.76 | TDP1 (0.37) | KDM4ELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3682440 | 0.74 | KDM4E (0.39) | KDM4ELMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL28607464 | 0.74 | RAB9A (0.39) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950830-A | Cyclic compound and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-04-03 | — | — | CN | disclosed |