Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20472107 | 1.00 | CHRM2 (0.57) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL29740550 | 1.00 | CHRM2 (0.57) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL27203458 | 1.00 | CHRM2 (0.57) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL17280821 | 0.95 | MAOB (0.56) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL8070917 | 0.93 | CHRM2 (0.58) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL30242673 | 0.91 | ALDH1A1 (0.59) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL28989527 | 0.91 | ALDH1A1 (0.59) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL10215924 | 0.91 | ALDH1A1 (0.59) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL14560517 | 0.91 | ALDH1A1 (0.59) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL1787317 | 0.86 | MAOB (0.56) | CHRM2MEN1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950890-B | Substituted imidazo [4,5-c ] quinoline macrocycles as multi-target kinase inhibitors | 北京赛林泰医药技术有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-110950890-A | Substituted imidazo [4,5-c ] quinoline macrocycles as multi-target kinase inhibitors | 北京赛林泰医药技术有限公司 | 2020-04-03 | — | — | CN | disclosed |