Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28375272 | 1.00 | GRIA4 (0.50) | GRIA4RXRARXRBMAPTKMT2A | |
| SCHEMBL11040137 | 0.83 | GRIA4 (0.34) | GRIA4CA1CA2 | |
| SCHEMBL7255641 | 0.81 | TAAR1 (0.45) | GRIA4 | |
| SCHEMBL7255639 | 0.81 | TAAR1 (0.45) | GRIA4 | |
| SCHEMBL7259968 | 0.81 | TAAR1 (0.45) | GRIA4 | |
| SCHEMBL11041736 | 0.80 | GRIA4 (0.45) | GRIA4TSHRCA1CA2ALDH1A1 | |
| SCHEMBL3659071 | 0.80 | MAPK1 (0.49) | GRIA4RXRARXRBMAPTKMT2A | |
| Alcohol SCHEMBL11040135 | 0.79 | GRIA4 (0.32) | GRIA4TSHRALDH1A1 | |
| SCHEMBL5877986 | 0.78 | PLCG1 (0.38) | GRIA4KMT2AALDH1A1 | |
| SCHEMBL5877993 | 0.78 | PLCG1 (0.38) | GRIA4KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922406-B | CGRP receptor antagonists | 伊兰科美国公司 | 2020-04-03 | — | — | CN | disclosed |