Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040137 | 0.96 | GRIA4 (0.34) | GRIA4STAT3 | |
| Alcohol SCHEMBL11041706 | 0.85 | ACHE (0.42) | GRIA4TSHRALDH1A1STAT3 | |
| SCHEMBL28375272 | 0.79 | GRIA4 (0.50) | GRIA4TSHRALDH1A1 | |
| SCHEMBL28375274 | 0.79 | GRIA4 (0.50) | GRIA4TSHRALDH1A1 | |
| SCHEMBL11041736 | 0.78 | GRIA4 (0.45) | GRIA4TSHRALDH1A1STAT3 | |
| SCHEMBL11040141 | 0.77 | GRIA4 (0.38) | GRIA4TSHRALDH1A1STAT3 | |
| SCHEMBL11857239 | 0.77 | CA1 (0.40) | GRIA4ALDH1A1 | |
| SCHEMBL5878353 | 0.73 | PLCG1 (0.38) | GRIA4ALDH1A1 | |
| SCHEMBL11958126 | 0.73 | CA1 (0.39) | GRIA4TSHRALDH1A1 | |
| SCHEMBL5877986 | 0.73 | PLCG1 (0.38) | GRIA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490165-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds, methods for preparing same and herbicidal use thereof | AMERICAN CYANAMID COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4308213-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds | AMERICAN CYANAMID COMPANY (US) | 1981-12-29 | — | — | US | disclosed |