Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 17/20 | 1.00 |
| ▸ | MAOB | P27338 | 6/20 | 0.68 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487592 | 0.81 | MAOA (1.00) | MAOAMAOBPOLLKDM4EPOLB | |
| SCHEMBL30487615 | 0.81 | MAOA (1.00) | MAOAMAOBPOLLKDM4EPOLB | |
| SCHEMBL28370465 | 0.79 | POLL (0.70) | MAOAMAOBPOLLKDM4EMAPT | |
| SCHEMBL16870295 | 0.79 | MAOA (0.68) | MAOAMAOB | |
| SCHEMBL16870362 | 0.76 | MAOA (0.61) | MAOAMAOB | |
| SCHEMBL11874566 | 0.75 | MAOA (0.60) | MAOAMAOBPOLL | |
| SCHEMBL28371042 | 0.72 | MAOA (1.00) | MAOAMAOB | |
| SCHEMBL27926131 | 0.71 | MAOA (0.55) | MAOAMAOBKDM4EPOLBMAPT | |
| SCHEMBL11874787 | 0.70 | MAOA (0.61) | MAOAMAOBPOLL | |
| SCHEMBL12621716 | 0.70 | MAOA (0.54) | MAOAMAOBPOLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872268-B | Isocoumarin derivative and preparation method and medicinal application thereof | 复旦大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-110872268-A | Isocoumarin derivative and preparation method and medicinal application thereof | 复旦大学 | 2020-03-10 | — | — | CN | disclosed |