Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16636595 | 0.83 | ERN1 (0.40) | ERN1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL28375373 | 0.81 | ERN1 (0.42) | ERN1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL14249510 | 0.80 | TAAR1 (0.39) | ERN1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL28385749 | 0.79 | FBP1 (0.45) | ERN1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL14249857 | 0.76 | KAT2B (0.37) | ERN1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL20582364 | 0.76 | PDGFRB (0.44) | ERN1ALDH1A1MAPTMAPK1MEN1 | |
| SCHEMBL29782441 | 0.74 | ERN1 (0.44) | ERN1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL16005316 | 0.74 | ERN1 (0.44) | ERN1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL17699766 | 0.74 | ERN1 (0.44) | ERN1ATMTDP1ALDH1A1HIF1A | |
| Ammonia Solution, Strong SCHEMBL28631510 | 0.73 | ERN1 (0.43) | ERN1ATMTDP1ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032658-B | 5-5 fused rings as C5a inhibitors | 凯莫森特里克斯股份有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-110997674-B | 6-5 fused rings as C5a inhibitors | 凯莫森特里克斯股份有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-111032658-A | 5-5 fused rings as C5a inhibitors | 凯莫森特里克斯股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-110997674-A | 6-5 fused rings as C5a inhibitors | 凯莫森特里克斯股份有限公司 | 2020-04-10 | — | — | CN | disclosed |