SCHEMBL28375571

SCHEMBL28375571

CCCCc1ccc(C)c(O)c1C(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.44
HTT P42858 3/20 0.38
MAPT P10636 3/20 0.38
ALOX5 P09917 2/20 0.38
CYP3A4 P08684 2/20 0.38
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CTRC Q99895 1/20 0.37
ELANE P08246 1/20 0.35
CTSG P08311 1/20 0.35
MAOA P21397 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
PTGS2 P35354 1/20 0.35
NPC1 O15118 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28358742 0.86 TYR (0.47) TYRHTTMAPTALOX5CYP3A4
SCHEMBL35794 0.83 TYR (0.43) TYRHTTMAPTALOX5CYP3A4
SCHEMBL3995610 0.80 TYR (0.55) TYRHTTMAPTALOX5CYP3A4
SCHEMBL1860671 0.80 CYP2C9 (0.43) TYRTP53GABRA1GABRB2ALDH1A1
SCHEMBL9074096 0.79 TYR (0.50) TYRHTTMAPTALOX5CYP3A4
SCHEMBL4083949 0.78 GABRA1 (0.39) CYP3A4MEN1TP53ALOX15TSHR
SCHEMBL62288 0.78 TYR (0.49) TYRHTTMAPTALOX5CYP3A4
SCHEMBL27820514 0.78 TYR (0.49) TYRHTTMAPTALOX5CYP3A4
SCHEMBL1006002 0.78 TYR (0.53) TYRHTTMAPTALOX5CYP3A4
SCHEMBL1846556 0.77 TYR (0.49) TYRHTTMAPTALOX5CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106831351-B Preparation method of bisphenol compound antioxidant 4,4' -propylene bis (3-methyl-6-tert-butylphenol) 河南师范大学 2020-03-10 CN disclosed