Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 4/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764454 | 0.96 | CASP1 (0.34) | CASP1MDM4TP53CASP3PTPN1 | |
| SCHEMBL20764453 | 0.96 | CASP1 (0.34) | CASP1MDM4TP53CASP3PTPN1 | |
| SCHEMBL20764509 | 0.86 | MDM4 (0.35) | MDM4TP53CASP3PTPN1MDM2 | |
| SCHEMBL20764508 | 0.86 | MDM4 (0.35) | MDM4TP53CASP3PTPN1MDM2 | |
| SCHEMBL22076699 | 0.80 | POLB (0.34) | — | |
| SCHEMBL22076701 | 0.80 | POLB (0.34) | — | |
| SCHEMBL22076742 | 0.80 | CD40 (0.40) | — | |
| SCHEMBL22076727 | 0.80 | CD40 (0.39) | — | |
| SCHEMBL22076728 | 0.80 | CD40 (0.39) | — | |
| SCHEMBL22076741 | 0.80 | CD40 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997627-A | Novel cystobacter amide derivatives | 亥姆霍兹感染研究中心有限公司 | 2020-04-10 | — | — | CN | disclosed |