SCHEMBL28376089

SCHEMBL28376089

CSc1nc(NC(=O)N(O)C(=O)[C@@H](N)C(C)C)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 2/20 0.50
▸ ADORA1 P30542 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.49
▸ PKM P14618 1/20 0.49
▸ SLC29A1 Q99808 1/20 0.47
▸ PGK1 P00558 1/20 0.47
▸ PGK2 P07205 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6765506 0.89 ADORA3 (0.49) ADORA3ADORA1KDM4EPKM
SCHEMBL28894183 0.86 ADORA3 (0.54) ADORA3ADORA1KDM4EPKMSLC29A1
SCHEMBL28894185 0.86 ADORA3 (0.54) ADORA3ADORA1KDM4EPKMSLC29A1
SCHEMBL28403790 0.86 ADORA2A (0.58) ADORA3ADORA1
SCHEMBL29238707 0.85 KDM4E (0.52) ADORA3KDM4EPKMSLC29A1CYP2C19
SCHEMBL29238705 0.85 KDM4E (0.52) ADORA3KDM4EPKMSLC29A1CYP2C19
SCHEMBL29278767 0.84 ADORA3 (0.59) ADORA3ADORA1KDM4EPKMPGK1
SCHEMBL31490447 0.83 KDM4E (0.54) ADORA3ADORA1KDM4EPKM
SCHEMBL1274809 0.83 ADORA3 (0.51) ADORA3ADORA1KDM4EPKMSLC29A1
SCHEMBL1274810 0.83 ADORA3 (0.51) ADORA3ADORA1KDM4EPKMSLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117413065-A Constructs, methods and uses for the preparation of circular RNAs 上海环码生物医药有限公司 2024-01-16 — — CN claimed
CN-113396219-B Purification of mRNA by tangential flow filtration ETHRIS GMBH (DE) 2026-05-26 — — CN disclosed
CN-120158444-A Negative selection method and system for purifying circular nucleic acid 上海环码生物医药有限公司 2025-06-17 — — CN disclosed
CN-120129688-A Efficient method for preparing highly purified 5' -capped oligonucleotides 垂林克生物技术有限公司 2025-06-10 — — CN disclosed
CN-120129532-A Stabilized lipid or lipid nanoparticle suspensions 埃泽瑞斯公司 2025-06-10 — — CN disclosed
CN-120082543-A Negative selection method and system for purifying circular nucleic acid 上海环码生物医药有限公司 2025-06-03 — — CN disclosed
CN-119768533-A Improved method for in vitro transcription 阿克丘勒斯治疗公司 2025-04-04 — — CN disclosed
CN-119768517-A Method and system for purifying circular nucleic acids 上海环码生物医药有限公司 2025-04-04 — — CN disclosed
CN-119656184-A Targeted delivery of modified RNAs 香港中文大学 2025-03-21 — — CN disclosed
CN-113423418-B Treatment of cilia disease 埃泽瑞斯公司 2025-01-10 — — CN disclosed
CN-115176005-A Compositions and methods for treating hemoglobinopathies 诺华股份有限公司 2022-10-11 — — CN disclosed
CN-114404581-A Cancer vaccine 摩登纳特斯有限公司 2022-04-29 — — CN disclosed
CN-108430456-B Cancer vaccine 摩登纳特斯有限公司 2022-01-18 — — CN disclosed
CN-113840926-A Method for preparing lipid-encapsulated RNA nanoparticles 阿克丘勒斯治疗公司 2021-12-24 — — CN disclosed
CN-113396219-A Purification of mRNA by tangential flow filtration 埃泽瑞斯公司 2021-09-14 — — CN disclosed
CN-112805386-A Plasmid containing a sequence encoding mRNA having a segmented poly (A) tail 埃泽瑞斯公司 2021-05-14 — — CN disclosed
CN-112105733-A Synthetic RIG-I like receptor agonists 查美特制药公司 2020-12-18 — — CN disclosed
CN-111848712-A End-capped nucleic acid molecules 诺华股份有限公司 2020-10-30 — — CN disclosed
CN-111246854-A Modified MRNA vaccines encoding herpes simplex virus glycoproteins and uses thereof 宾夕法尼亚大学理事会 2020-06-05 — — CN disclosed
CN-110891553-A Method for producing liposome encapsulating RNA 葛兰素史密丝克莱恩生物有限公司 2020-03-17 — — CN disclosed
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