Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.56 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10255802 | 0.91 | DDB1 (0.45) | DDB1CRBNWNT3APIK3CAPRKDC | |
| SCHEMBL29742108 | 0.84 | CCND1 (0.48) | FASN | |
| SCHEMBL1392785 | 0.84 | CCND1 (0.48) | FASN | |
| SCHEMBL10256044 | 0.84 | WNT3A (0.48) | WNT3AMAPTALKGPR119HTT | |
| SCHEMBL15008006 | 0.84 | DDB1 (0.52) | DDB1CRBNWNT3APIK3CAPRKDC | |
| SCHEMBL10256055 | 0.82 | PIK3CA (0.42) | DDB1CRBNPIK3CAPRKDCMTOR | |
| SCHEMBL30512276 | 0.82 | PIK3CA (0.42) | DDB1CRBNPIK3CAPRKDCMTOR | |
| SCHEMBL608702 | 0.82 | DDB1 (0.56) | DDB1CRBNWNT3APIK3CAPRKDC | |
| SCHEMBL14926052 | 0.82 | PIK3CA (0.43) | DDB1CRBNPIK3CAPRKDCMTOR | |
| SCHEMBL12177860 | 0.81 | DDB1 (0.46) | DDB1CRBNWNT3APIK3CAPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818724-B | Pyridone and azapyridone compounds and methods of use | 吉利德康涅狄格有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-107253963-B | Pyridone and azapyridone compounds and methods of use | 吉利德康涅狄格有限公司 | 2020-04-14 | — | — | CN | disclosed |
| CN-110818724-A | Pyridone and azapyridone compounds and methods of use | 吉利德康涅狄格有限公司 | 2020-02-21 | — | — | CN | disclosed |