Acetone

Acetone

SCHEMBL28376337

CC(C)=O.CC(C)=O.CC(C)=O.O=CC(O)CO

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.78
OR51E2 Q9H255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PAX8 Q06710 1/20 0.33
GAPDH P04406 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL1711073 1.00 AKR1B1 (0.78) AKR1B1OR51E2TDP1LMNAALDH1A1
Acetone SCHEMBL5567209 1.00 AKR1B1 (0.78) AKR1B1OR51E2TDP1LMNAALDH1A1
Acetone SCHEMBL9466071 1.00 AKR1B1 (0.78) AKR1B1OR51E2TDP1LMNAALDH1A1
Acetone SCHEMBL2871076 1.00 AKR1B1 (0.78) AKR1B1OR51E2TDP1LMNAALDH1A1
Acetone SCHEMBL27957990 0.93 AKR1B1 (0.67) AKR1B1PAX8
SCHEMBL8440817 0.90 AKR1B1 (0.70) AKR1B1OR51E2TDP1ALDH1A1PAX8
Mannitol SCHEMBL10506495 0.89 AKR1B1 (0.61) AKR1B1TDP1LMNAPAX8
SCHEMBL19505 0.88
SCHEMBL2121317 0.88
SCHEMBL22045 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108610322-B Preparation method of R-glyceraldehyde acetonide 江苏八巨药业有限公司 2020-04-07 CN disclosed