Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.78 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL5567209 | 1.00 | AKR1B1 (0.78) | AKR1B1OR51E2TDP1LMNAALDH1A1 | |
| Acetone SCHEMBL28376337 | 1.00 | AKR1B1 (0.78) | AKR1B1OR51E2TDP1LMNAALDH1A1 | |
| Acetone SCHEMBL9466071 | 1.00 | AKR1B1 (0.78) | AKR1B1OR51E2TDP1LMNAALDH1A1 | |
| Acetone SCHEMBL2871076 | 1.00 | AKR1B1 (0.78) | AKR1B1OR51E2TDP1LMNAALDH1A1 | |
| Acetone SCHEMBL27957990 | 0.93 | AKR1B1 (0.67) | AKR1B1PAX8 | |
| SCHEMBL8440817 | 0.90 | AKR1B1 (0.70) | AKR1B1OR51E2TDP1ALDH1A1PAX8 | |
| Mannitol SCHEMBL10506495 | 0.89 | AKR1B1 (0.61) | AKR1B1TDP1LMNAPAX8 | |
| SCHEMBL19505 | 0.88 | — | — | |
| SCHEMBL2121317 | 0.88 | — | — | |
| SCHEMBL22045 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752309-B | Method for synthesizing glyceraldehyde acetonide through catalytic oxidation | 扬州工业职业技术学院 | 2020-03-31 | — | — | CN | claimed |
| CN-106632282-B | The fluorine-containing amides compound of 1,3- dimethyl -7- substituted quinazoline -2,4- diketone and its synthetic method and application | 重庆智合生物医药有限公司 | 2019-09-20 | — | — | CN | claimed |
| CN-109748893-A | A method of gemcitabine intermediate is prepared using chiral catalyst | 江苏八巨药业有限公司 | 2019-05-14 | — | — | CN | claimed |
| CN-109298122-A | A kind of detection method of R- glyceraldehyde acetonide finished product purity | 上海康鹏科技有限公司 | 2019-02-01 | — | — | CN | claimed |
| CN-108752309-A | A kind of method of catalysis oxidation synthetic glycerine aldehyde contracting acetone | 扬州工业职业技术学院 | 2018-11-06 | — | — | CN | claimed |
| CN-106632282-A | 1,3-dimethyl-7-substituted quinazoline-2,4-dione fluorine-containing amide compound and synthesizing method and application thereof | 重庆智合生物医药有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-105566406-A | Preparation method of fluorodesoxyribofuranose | JIANGXI SHENGFU CHEMICAL CO LTD | 2016-05-11 | — | — | CN | claimed |
| CN-104788419-A | Chiral (2, 2-dimethyl-1, 3-dioxolane-4-yl) hydroxymethanesulfonate, and preparation method and application thereof | UNIV XIHUA | 2015-07-22 | — | — | CN | claimed |
| US-20140031562-A1 | Method for Forming Allylic Alcohols | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI (US) | 2014-01-30 | — | — | US | claimed |
| CN-102311418-B | Preparation method for benzodihydropyran compound | CHENGDU KANGHONG PHARMACEUTICALS GROUP CO LTD | 2013-12-25 | — | — | CN | claimed |
| CN-102311418-A | Preparation method for benzodihydropyran compound | CHENGDU KANGHONG PHARMACEUTICALS GROUP CO LTD | 2012-01-11 | — | — | CN | claimed |
| WO-2010025366-A2 | METHOD FOR FORMING ALLYLIC ALCOHOLS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-03-04 | — | — | WO | claimed |
| EP-1678158-B1 | PROCESS FOR THE PREPARATION OF GLYCERALDEHYDE ACETONIDE | DSM IP ASSETS BV (NL) | 2008-03-26 | — | — | EP | claimed |
| US-20070129553-A1 | Process for the preparation of glyceraldehyde acetonide | DSM IP ASSETS B.V. (NL) | 2007-06-07 | — | — | US | claimed |
| EP-1678158-A1 | PROCESS FOR THE PREPARATION OF GLYCERALDEHYDE ACETONIDE | DSM IP Assets B.V. (NL) | 2006-07-12 | — | — | EP | claimed |
| EP-1673364-A1 | PROCESS FOR THE PREPARATION OF (S)-GLYCERALDEHYDE ACETONIDE | DSM IP Assets B.V. (NL) | 2006-06-28 | — | — | EP | claimed |
| WO-2005040149-A1 | PROCESS FOR THE PREPARATION OF GLYCERALDEHYDE ACETONIDE | DSM IP ASSETS B.V. (NL) | 2005-05-06 | — | — | WO | claimed |
| WO-2005037819-A1 | PROCESS FOR THE PREPARATION OF (S)-GLYCERALDEHYDE ACETONIDE | DSM IP ASSETS B.V. (NL) | 2005-04-28 | — | — | WO | claimed |
| US-4413142-A | MULTISTAGE, D-MANNITOL, KETONE | ANIC S.P.A. (IT) | 1983-11-01 | — | — | US | claimed |
| EP-0060595-A2 | Method for preparing L-carnitine | ANIC S.p.A. (IT) | 1982-09-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031562-A1 | Method for Forming Allylic Alcohols | ADH1A, ADH1C, ADH5 | AKR1B1 59/4885OR51E2 534/4885TDP1 2911/4885 |
| US-20070129553-A1 | Process for the preparation of glyceraldehyde acetonide | CA5A, GCG, CA5B | AKR1B1 70/4885OR51E2 1422/4885TDP1 1519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.