SCHEMBL283768

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10128266	0.93	SYK (0.40)	SYKHTR2BHTR1AHTR2AHTR2C
	SCHEMBL10128272	0.91	ESR1 (0.42)	SYKHTR2BHTR1AHTR2AHTR2C
	SCHEMBL10157413	0.89	SYK (0.40)	SYKHTR2BHTR1AHTR2AHTR2C
	SCHEMBL10128349	0.87	CAMK1D (0.43)	SYKPIK3CD
	SCHEMBL10128675	0.86	SYK (0.38)	SYKBCDIN3D
	SCHEMBL16305358	0.86	SYK (0.38)	SYK
	SCHEMBL10158120	0.86	MAPK14 (0.37)	SYK
	SCHEMBL10157288	0.85	SYK (0.38)	SYKINSRGRK2BCDIN3DSCN9A
	SCHEMBL10128339	0.85	TNNI3K (0.42)	SYK
	SCHEMBL10128414	0.85	SYK (0.38)	SYKINSRBCDIN3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.