Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044915 | 0.82 | KDM4E (0.53) | CYP1A2KDM4ESTAT3HIF1ANPC1 | |
| SCHEMBL28377726 | 0.77 | CYP1A2 (0.47) | CYP1A2KDM4ESTAT3HIF1ANPC1 | |
| SCHEMBL25863815 | 0.77 | CYP1A2 (0.61) | CYP1A2KDM4ESTAT3HIF1ANPC1 | |
| SCHEMBL23908921 | 0.73 | KDM4E (0.51) | CYP1A2KDM4ESTAT3HIF1ANPC1 | |
| SCHEMBL5820415 | 0.72 | KDM4E (0.53) | CYP1A2KDM4ESTAT3HIF1AYTHDC1 | |
| SCHEMBL1574055 | 0.71 | KDM4E (0.46) | CYP1A2KDM4ESTAT3HIF1ANPC1 | |
| SCHEMBL11806739 | 0.71 | POLB (0.64) | CYP1A2KDM4ESTAT3HIF1ANPC1 | |
| SCHEMBL1563249 | 0.70 | KDM4E (0.50) | CYP1A2KDM4ESTAT3HIF1ANPC1 | |
| SCHEMBL23914755 | 0.69 | KDM4E (0.50) | CYP1A2KDM4ESTAT3HIF1ANPC1 | |
| SCHEMBL14698771 | 0.69 | KDM4E (0.49) | CYP1A2KDM4ESTAT3HIF1ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869359-A | Novel compounds and pharmaceutical compositions thereof for the treatment of fibrosis | 加拉帕戈斯股份有限公司 | 2020-03-06 | — | — | CN | disclosed |