Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.73 |
| ▸ | CA1 | P00915 | 12/20 | 0.67 |
| ▸ | CA9 | Q16790 | 12/20 | 0.67 |
| ▸ | CA12 | O43570 | 10/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.67 |
| ▸ | CA7 | P43166 | 3/20 | 0.67 |
| ▸ | CA4 | P22748 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | CA3 | P07451 | 2/20 | 0.67 |
| ▸ | CA6 | P23280 | 2/20 | 0.67 |
| ▸ | CA5A | P35218 | 2/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | PARP1 | P09874 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzenesulfonamide SCHEMBL11874144 | 0.88 | CA2 (0.58) | CA2CA1CA9CA12CA14 | |
| P-Toluenesulfonamide SCHEMBL7641434 | 0.87 | CA2 (0.67) | CA2CA1CA9CA12CA14 | |
| Benzenesulfonamide SCHEMBL27896159 | 0.87 | CA2 (0.80) | CA2CA1CA9CA12CA14 | |
| Benzenesulfonamide SCHEMBL3971272 | 0.87 | CA2 (0.80) | CA2CA1CA9CA12CA14 | |
| Benzenesulfonamide SCHEMBL19348104 | 0.87 | CA2 (0.80) | CA2CA1CA9CA12CA14 | |
| SCHEMBL176891 | 0.85 | CA2 (1.00) | CA2CA1CA9CA12CA14 | |
| Benzenesulfonamide SCHEMBL9491339 | 0.84 | CA2 (0.84) | CA2CA1CA9CA12CA14 | |
| Benzamide SCHEMBL29602973 | 0.84 | PARP1 (0.94) | CA2CYP2C19POLBCYP3A4PARP1 | |
| Benzamide SCHEMBL29958827 | 0.83 | TSHR (0.67) | CA2CA1CA9CA12CA14 | |
| Benzamide SCHEMBL29958812 | 0.83 | TSHR (0.67) | CA2CA1CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111228250-B | Application of 2-benzenesulfonylamino benzamide compound in preparation of medicine for treating liver cancer | 中国医学科学院医药生物技术研究所 | 2021-02-09 | — | — | CN | claimed |
| CN-111228250-A | Application of 2-benzenesulfonylamino benzamide compound in preparation of medicine for treating liver cancer | 中国医学科学院医药生物技术研究所 | 2020-06-05 | — | — | CN | claimed |
| CN-110840836-B | Benzamide compound IMB16-4 nano suspension and preparation method thereof | 中国医学科学院医药生物技术研究所 | 2021-11-26 | — | — | CN | disclosed |
| CN-111228250-B | Application of 2-benzenesulfonylamino benzamide compound in preparation of medicine for treating liver cancer | 中国医学科学院医药生物技术研究所 | 2021-02-09 | — | — | CN | disclosed |
| CN-111228250-A | Application of 2-benzenesulfonylamino benzamide compound in preparation of medicine for treating liver cancer | 中国医学科学院医药生物技术研究所 | 2020-06-05 | — | — | CN | disclosed |
| CN-110840836-A | Benzamide compound IMB16-4 nano suspension and preparation method thereof | 中国医学科学院医药生物技术研究所 | 2020-02-28 | — | — | CN | disclosed |