Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174283 | 0.93 | RECQL (0.39) | RECQLKDM4ETSHRALDH1A1TDP1 | |
| SCHEMBL4073630 | 0.76 | RECQL (0.71) | RECQLKDM4ETSHRALDH1A1TDP1 | |
| SCHEMBL26089966 | 0.75 | MEN1 (0.42) | RECQLKDM4ETSHRALDH1A1TDP1 | |
| SCHEMBL28374814 | 0.73 | DPP4 (0.37) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL22890548 | 0.70 | KDM4E (0.41) | RECQLKDM4ETSHRALDH1A1HPGD | |
| SCHEMBL29177255 | 0.69 | KMT2A (0.37) | KDM4ETSHRALDH1A1TDP1HPGD | |
| SCHEMBL30370553 | 0.69 | KDM4E (0.55) | RECQLKDM4EALDH1A1TDP1HPGD | |
| SCHEMBL553686 | 0.69 | KDM4E (0.55) | RECQLKDM4EALDH1A1TDP1HPGD | |
| SCHEMBL1625883 | 0.69 | KDM4E (0.46) | RECQLKDM4ETSHRALDH1A1TDP1 | |
| SCHEMBL4066614 | 0.68 | KDM4E (0.64) | RECQLKDM4ETSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396474-A | Plasma kallikrein inhibitors | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |
| CN-106061480-B | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2020-02-28 | — | — | CN | disclosed |