Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177255 | 0.89 | KMT2A (0.37) | MEN1KMT2ATSHRUPP1KDM4E | |
| SCHEMBL29177294 | 0.81 | MEN1 (0.39) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL9721680 | 0.78 | KMT2A (0.50) | MEN1KMT2ATSHRALDH1A1TDP1 | |
| SCHEMBL28823338 | 0.76 | KMT2A (0.48) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL26090155 | 0.75 | MGLL (0.45) | MEN1KMT2AMAPT | |
| SCHEMBL28378653 | 0.75 | RECQL (0.44) | MEN1KMT2ATSHRUPP1KDM4E | |
| SCHEMBL20152482 | 0.75 | KMT2A (0.51) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL29177225 | 0.75 | KMT2A (0.47) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL17664154 | 0.75 | TSHR (0.44) | MEN1KMT2ATSHRUPP1KDM4E | |
| SCHEMBL29177218 | 0.74 | KMT2A (0.47) | MEN1KMT2ATSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |