SCHEMBL283787

SCHEMBL283787

COc1cccc(C(N)=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 3/20 1.00
CES2 O00748 1/20 0.71
CES1 P23141 1/20 0.71
PRSS1 P07477 1/20 0.67
PRSS2 P07478 1/20 0.67
PRSS3 P35030 1/20 0.67
STS P08842 2/20 0.63
PARP10 Q53GL7 2/20 0.62
PARP2 Q9UGN5 2/20 0.62
TNKS O95271 1/20 0.62
PARP15 Q460N3 1/20 0.62
PARP14 Q460N5 1/20 0.62
TNKS2 Q9H2K2 1/20 0.62
NPC1 O15118 5/20 0.59
RAB9A P51151 4/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
PARP4 Q9UKK3 1/20 0.59
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29503138 1.00 PARP1 (1.00) PARP1CES2CES1PRSS1PRSS2
Hydrochloric Acid SCHEMBL4377519 0.98 PARP1 (0.96) PARP1CES2CES1PRSS1PRSS2
Hydrochloric Acid SCHEMBL407554 0.98 PARP1 (0.96) PARP1CES2CES1PRSS1PRSS2
Acetic Acid SCHEMBL4630445 0.94 PARP1 (0.89) PARP1CES2CES1PRSS1PRSS2
SCHEMBL7050338 0.93 PARP1 (0.86) PARP1CES2CES1PRSS1PRSS2
Terephthalamic Acid SCHEMBL7678892 0.90 PARP1 (0.81) PARP1CES2CES1PRSS1PRSS2
SCHEMBL1690557 0.89 PARP1 (0.80) PARP1CES2CES1PRSS1PRSS2
Trifluoroacetic Acid SCHEMBL28214522 0.88 PARP1 (0.78) PARP1CES2CES1PRSS1PRSS2
SCHEMBL13687397 0.88 PARP10 (0.78) PARP1CES2CES1PRSS1PRSS2
SCHEMBL28515342 0.87 PARP1 (0.76) PARP1CES2CES1PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1879 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12575248-B2 Zinc oxide nanomaterial and preparation method thereof and semiconductor device TCL TECHNOLOGY GROUP CORPORATION (CN) 2026-03-10 US claimed
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed
EP-4640686-A1 DEGRADER FOR DEGRADING BRD PROTEIN AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Innocure Therapeutics, Inc. (KR) 2025-10-29 EP claimed
CN-119504475-A N-alkylamine compound, preparation method and application 南阳师范学院 2025-02-25 CN claimed
EP-4167307-B1 ZINC OXIDE NANOMATERIAL AND PREPARATION METHOD THEREFOR, AND SEMICONDUCTOR DEVICE TCL TECH GROUP CORP (CN) 2025-02-05 EP claimed
CN-119371298-A Method for efficiently synthesizing indenone compound 南阳师范学院 2025-01-28 CN claimed
CN-115413278-B Pyrimidine derivative and composition for preventing or treating neurodegenerative disease and cancer comprising same 丸仁制药株式会社 2025-01-10 CN claimed
CN-118344283-A Trifluoromethyl unit-containing substituted 2-piperidone compound and synthesis method thereof 西南交通大学 2024-07-16 CN claimed
CN-116925562-B Anthraquinone dye for color photoresist and application of anthraquinone dye in color photoresist and optical filter 大连理工大学 2024-06-25 CN claimed
WO-2024112122-A1 DEGRADER FOR DEGRADING BRD PROTEIN AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 WO claimed
US-5985867-A TREATING HIV INFECTION DUPONT PHARMACEUTICALS COMPANY (US) 1999-11-16 US claimed
US-5874444-A CONTROLLING CELL AGING GERON CORPORATION (US) 1999-02-23 US claimed
WO-1998043969-A1 INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS DUPONT PHARMACEUTICALS COMPANY (US) 1998-10-08 WO claimed
WO-1998027975-A1 POLY(ADP-RIBOSE) POLYMERASE INHIBITORS TO TREAT DISEASES ASSOCIATED WITH CELLULAR SENESCENCE GERON CORPORATION (US) 1998-07-02 WO claimed
EP-0775110-A1 ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS WARNER-LAMBERT COMPANY (US) 1997-05-28 EP claimed
EP-0531370-B1 INHIBITION OF VIRAL INFECTION BRITISH TECH GROUP (GB) 1996-09-18 EP claimed
WO-1996004242-A1 ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS WARNER-LAMBERT COMPANY (US) 1996-02-15 WO claimed
EP-0531370-A1 INHIBITION OF VIRAL INFECTION. COLLINS MARY KATHARINE LEVINGE (GB) 1993-03-17 EP claimed
WO-1991018591-A1 INHIBITION OF VIRAL INFECTION COLLINS MARY KATHARINE LEVINGE (GB) 1991-12-12 WO claimed
US-3943152-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12575248-B2 Zinc oxide nanomaterial and preparation method thereof and semiconductor device ZRANB2, ZKSCAN2, SLC39A3 PARP1 3305/4885CES2 2168/4885CES1 3816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.