SCHEMBL28515342

SCHEMBL28515342

C1CCPC1.COc1cccc(C(N)=O)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.76
CES2 O00748 1/20 0.56
CES1 P23141 1/20 0.56
PRSS1 P07477 1/20 0.53
PRSS2 P07478 1/20 0.53
PRSS3 P35030 1/20 0.53
STS P08842 2/20 0.51
PARP10 Q53GL7 2/20 0.50
PARP2 Q9UGN5 2/20 0.50
TNKS O95271 1/20 0.50
PARP15 Q460N3 1/20 0.50
PARP14 Q460N5 1/20 0.50
TNKS2 Q9H2K2 1/20 0.50
NPC1 O15118 3/20 0.48
RAB9A P51151 2/20 0.48
CHRNA1 P02708 1/20 0.47
CHRNG P07510 1/20 0.47
CHRNB1 P11230 1/20 0.47
CHRNB2 P17787 1/20 0.47
SLC6A2 P23975 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29503138 0.87 PARP1 (1.00) PARP1CES2CES1PRSS1PRSS2
SCHEMBL283787 0.87 PARP1 (1.00) PARP1CES2CES1PRSS1PRSS2
Hydrochloric Acid SCHEMBL4377519 0.85 PARP1 (0.96) PARP1CES2CES1PRSS1PRSS2
Hydrochloric Acid SCHEMBL407554 0.85 PARP1 (0.96) PARP1CES2CES1PRSS1PRSS2
Acetic Acid SCHEMBL4630445 0.82 PARP1 (0.89) PARP1CES2CES1PRSS1PRSS2
SCHEMBL7050338 0.81 PARP1 (0.86) PARP1CES2CES1PRSS1PRSS2
SCHEMBL28503916 0.81 PARP10 (0.72) PARP1CES2CES1PRSS1PRSS2
Terephthalamic Acid SCHEMBL7678892 0.78 PARP1 (0.81) PARP1CES2CES1PRSS1PRSS2
SCHEMBL27764421 0.78 PARP1 (0.73) PARP1CES2CES1PRSS1PRSS2
SCHEMBL27764397 0.78 PARP1 (0.73) PARP1CES2CES1PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109762017-B Preparation method of iron-catalyzed phosphazene compound 大连理工大学 2021-06-18 CN disclosed
CN-112142792-A Novel method for constructing nitrogen-phosphorus double bonds through visible light catalysis 大连理工大学 2020-12-29 CN disclosed