Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 12/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.48 |
| ▸ | CDK2 | P24941 | 11/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.47 |
| ▸ | CDK9 | P50750 | 6/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.47 |
| ▸ | CDK1 | P06493 | 11/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.46 |
| ▸ | CLK2 | P49760 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.46 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.46 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148791 | 0.80 | CDK2 (0.49) | KDM4ENPC1MAPTTDP1CDK5 | |
| SCHEMBL28378829 | 0.79 | KDM4E (0.52) | KDM4ENPC1MAPTTDP1CDK5 | |
| SCHEMBL30148790 | 0.76 | KDM4E (0.50) | KDM4ENPC1MAPTTDP1CDK5 | |
| SCHEMBL30148780 | 0.67 | CDK1 (0.55) | KDM4ENPC1MAPTTDP1CDK5 | |
| SCHEMBL31069517 | 0.66 | TDP1 (0.87) | KDM4ENPC1MAPTTDP1CDK5 | |
| Myoseverin SCHEMBL29376276 | 0.66 | TDP1 (1.00) | KDM4ENPC1MAPTTDP1CDK5 | |
| Myoseverin SCHEMBL13325947 | 0.66 | TDP1 (1.00) | KDM4ENPC1MAPTTDP1CDK5 | |
| SCHEMBL14403894 | 0.65 | CDK1 (0.88) | KDM4ENPC1MAPTTDP1CDK5 | |
| SCHEMBL30148821 | 0.65 | CDK1 (0.55) | KDM4ENPC1MAPTTDP1CDK5 | |
| SCHEMBL16322125 | 0.65 | KDM4E (0.79) | KDM4ENPC1MAPTTDP1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903289-A | Purine-aminomethyl-pyridone derivative, preparation method and application thereof | 四川大学 | 2020-03-24 | — | — | CN | disclosed |