Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.61 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.47 |
| ▸ | FDPS | P14324 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137487 | 0.86 | LPAR3 (0.61) | LPAR3LPAR1LPAR2SMPD1GGPS1 | |
| SCHEMBL258171 | 0.81 | LPAR3 (0.63) | LPAR3LPAR1LPAR2SMPD1GGPS1 | |
| SCHEMBL28687765 | 0.80 | LPAR3 (0.62) | LPAR3LPAR1LPAR2SMPD1GGPS1 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL28883739 | 0.79 | LPAR3 (0.95) | LPAR3LPAR1LPAR2SMPD1 | |
| Hexadecyl Dihydrogen Phosphate SCHEMBL27692367 | 0.79 | LPAR3 (0.95) | LPAR3LPAR1LPAR2SMPD1 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL65138 | 0.77 | LPAR3 (1.00) | LPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL3857929 | 0.77 | LPAR3 (1.00) | LPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL258319 | 0.77 | LPAR3 (1.00) | LPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL1191894 | 0.77 | LPAR3 (1.00) | LPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL22325599 | 0.77 | LPAR3 (1.00) | LPAR3LPAR1LPAR2SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110655546-B | Sofosbuvir derivative, and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-110655546-A | Sofosbuvir derivative and preparation method and application thereof | 安徽贝克联合制药有限公司 | 2020-01-07 | — | — | CN | disclosed |