Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28379777 | 1.00 | ADORA2B (0.53) | ADORA2BADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7309668 | 0.87 | ADORA2B (0.50) | ADORA2BADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7309679 | 0.87 | ADORA2B (0.50) | ADORA2BADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7305598 | 0.86 | KDM4E (0.51) | ADORA2BADORA1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7305607 | 0.86 | KDM4E (0.51) | ADORA2BADORA1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7304436 | 0.85 | ADORA2B (0.63) | ADORA2BADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7304425 | 0.85 | ADORA2B (0.63) | ADORA2BADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL7305751 | 0.85 | KDM4E (0.50) | ADORA2BADORA1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7305762 | 0.85 | KDM4E (0.50) | ADORA2BADORA1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7307067 | 0.85 | ADORA2B (0.50) | ADORA2BADORA1KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018856-B | 8-substituted styrylxanthine derivatives and uses thereof | 广东东阳光药业有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-111018856-A | 8-substituted styrylxanthine derivatives and uses thereof | 广东东阳光药业有限公司 | 2020-04-17 | — | — | CN | disclosed |