SCHEMBL28379989

SCHEMBL28379989

O=C=Nc1cc2ccccc2c(-c2cccc3ccccc23)c1N=C=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.39
CES1 P23141 1/20 0.39
CYP3A4 P08684 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
ABCB11 O95342 1/20 0.36
NR3C1 P04150 1/20 0.36
CYP1A2 P05177 1/20 0.36
ADRA2A P08913 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
ALOX15 P16050 1/20 0.36
ADRA2C P18825 1/20 0.36
MAOA P21397 1/20 0.36
DRD1 P21728 1/20 0.36
SLC6A4 P31645 1/20 0.36
HTR2B P41595 1/20 0.36
CCR2 P41597 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112471 0.79 POLB (0.41) CYP3A4ALDH1A1HPGDHSD17B10ABCB11
SCHEMBL5971050 0.76 CYP3A4 (0.47) GPR84CYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL109502 0.75 CYP3A4 (0.47) CYP3A4ALDH1A1HPGDHSD17B10ABCB11
SCHEMBL6541648 0.73 CES1 (0.42) GPR84CES1ALDH1A1HPGDHSD17B10
SCHEMBL29642615 0.72 ALDH1A1 (0.42) GPR84CES1CYP3A4ALDH1A1HPGD
SCHEMBL17787466 0.72 ALDH1A1 (0.42) GPR84CES1CYP3A4ALDH1A1HPGD
SCHEMBL6858063 0.72 CYP1A2 (0.43) CYP3A4ALDH1A1HPGDHSD17B10ABCB11
Alpha-Naphthylisocyanate SCHEMBL374 0.71 CYP1A2 (0.64) CYP3A4ALDH1A1HPGDHSD17B10ABCB11
Alpha-Naphthylisocyanate SCHEMBL29400034 0.71 CYP1A2 (0.64) CYP3A4ALDH1A1HPGDHSD17B10ABCB11
SCHEMBL3713908 0.71 ALDH1A1 (0.42) GPR84CES1CYP3A4ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110997851-B Allyl-functionalized urethane oligomers and related compositions for coatings and adhesives 阿科玛法国公司 2022-06-07 CN disclosed
CN-110997851-A Allyl-functionalized urethane oligomers and related compositions for coatings and adhesives 阿科玛法国公司 2020-04-10 CN disclosed