Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.74 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.74 |
| ▸ | BCR | P11274 | 9/20 | 0.74 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.74 |
| ▸ | KIT | P10721 | 5/20 | 0.74 |
| ▸ | PRKCA | P17252 | 2/20 | 0.74 |
| ▸ | EGFR | P00533 | 2/20 | 0.73 |
| ▸ | JAK3 | P52333 | 1/20 | 0.65 |
| ▸ | BTK | Q06187 | 1/20 | 0.65 |
| ▸ | ITK | Q08881 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841120 | 0.88 | ABL1 (0.79) | ABL1PDGFRABCRPDGFRBKIT | |
| SCHEMBL3219529 | 0.87 | ABL1 (0.77) | ABL1PDGFRABCRPDGFRBKIT | |
| SCHEMBL13492488 | 0.86 | ABL1 (0.76) | ABL1PDGFRABCRPDGFRBKIT | |
| SCHEMBL20602916 | 0.86 | ABL1 (0.77) | ABL1PDGFRABCRPDGFRBKIT | |
| SCHEMBL4897200 | 0.85 | PDGFRA (0.88) | ABL1PDGFRABCRPDGFRBKIT | |
| SCHEMBL723757 | 0.85 | PDGFRA (1.00) | ABL1PDGFRABCRPDGFRBKIT | |
| SCHEMBL9666 | 0.85 | PDGFRA (1.00) | ABL1PDGFRABCRPDGFRBKIT | |
| SCHEMBL9782 | 0.85 | PDGFRA (1.00) | ABL1PDGFRABCRPDGFRBKIT | |
| SCHEMBL29498750 | 0.85 | PDGFRA (1.00) | ABL1PDGFRABCRPDGFRBKIT | |
| SCHEMBL1408817 | 0.84 | ABL1 (0.74) | ABL1PDGFRABCRPDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111039921-A | Synthesis process of imatinib and imatinib mesylate | 杭州沧海帆医药科技有限公司 | 2020-04-21 | — | — | CN | disclosed |