Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.79 |
| ▸ | PDGFRA | P16234 | 11/20 | 0.79 |
| ▸ | BCR | P11274 | 9/20 | 0.79 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.79 |
| ▸ | PRKCA | P17252 | 3/20 | 0.79 |
| ▸ | EGFR | P00533 | 2/20 | 0.78 |
| ▸ | JAK3 | P52333 | 1/20 | 0.69 |
| ▸ | BTK | Q06187 | 1/20 | 0.69 |
| ▸ | ITK | Q08881 | 1/20 | 0.69 |
| ▸ | KIT | P10721 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13492488 | 0.91 | ABL1 (0.76) | ABL1PDGFRABCRPDGFRBPRKCA | |
| SCHEMBL3219529 | 0.90 | ABL1 (0.77) | ABL1PDGFRABCRPDGFRBPRKCA | |
| SCHEMBL13492489 | 0.89 | ABL1 (0.75) | ABL1PDGFRABCRPDGFRBPRKCA | |
| SCHEMBL9666 | 0.88 | PDGFRA (1.00) | ABL1PDGFRABCRPDGFRBPRKCA | |
| SCHEMBL9782 | 0.88 | PDGFRA (1.00) | ABL1PDGFRABCRPDGFRBPRKCA | |
| SCHEMBL29498750 | 0.88 | PDGFRA (1.00) | ABL1PDGFRABCRPDGFRBPRKCA | |
| SCHEMBL1408817 | 0.88 | ABL1 (0.74) | ABL1PDGFRABCRPDGFRBPRKCA | |
| SCHEMBL28381450 | 0.88 | ABL1 (0.74) | ABL1PDGFRABCRPDGFRBPRKCA | |
| SCHEMBL13492322 | 0.87 | ABL1 (0.73) | ABL1PDGFRABCRPDGFRBPRKCA | |
| SCHEMBL12901730 | 0.87 | ABL1 (0.67) | ABL1PDGFRABCRPDGFRBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102212057-B | Carboxylic acid non-steroidal anti-inflammatory agent derivative and preparation method and application thereof | UNIV HEFEI TECHNOLOGY | 2013-11-27 | — | — | CN | disclosed |
| CN-102212057-A | Carboxylic acid non-steroidal anti-inflammatory agent derivative and preparation method and application thereof | UNIV HEFEI TECHNOLOGY | 2011-10-12 | — | — | CN | disclosed |