Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28887186 | 0.89 | PTGDR2 (0.41) | LMNAPTGDR2 | |
| SCHEMBL12466468 | 0.86 | LMNA (0.48) | LMNAMEN1KMT2APTGDR2P2RX7 | |
| SCHEMBL27938730 | 0.85 | PTGDR2 (0.44) | LMNAMEN1KMT2APTGDR2HTT | |
| SCHEMBL27919901 | 0.83 | LMNA (0.48) | LMNAMEN1KMT2APTGDR2MAPT | |
| SCHEMBL27938535 | 0.82 | LMNA (0.54) | LMNAMEN1KMT2APTGDR2HTT | |
| SCHEMBL508780 | 0.80 | LMNA (0.49) | LMNAMEN1KMT2APTGDR2MAPT | |
| SCHEMBL27938399 | 0.80 | LMNA (0.56) | LMNAMEN1KMT2APTGDR2MAPT | |
| SCHEMBL27919902 | 0.79 | LMNA (0.48) | LMNAMEN1KMT2AMAPTHTT | |
| SCHEMBL28382130 | 0.76 | LMNA (0.48) | LMNAMEN1KMT2AMAPTHTT | |
| SCHEMBL12466137 | 0.74 | PTGDR2 (0.45) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011332-B | Pyrazole compounds as CRTH2 antagonists | GB007公司 | 2020-03-13 | — | — | CN | disclosed |