Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28383021 | 0.87 | BCHE (0.71) | MAPTMAPK1LMNAHPGDNPC1 | |
| SCHEMBL7101080 | 0.86 | MAPT (0.58) | MAPTMAPK1LMNAHPGDNPC1 | |
| SCHEMBL28383313 | 0.86 | MAPT (0.58) | MAPTMAPK1LMNAHPGDNPC1 | |
| SCHEMBL29843588 | 0.86 | MAPT (0.58) | MAPTMAPK1LMNAHPGDNPC1 | |
| SCHEMBL3498432 | 0.84 | BCHE (0.63) | MAPTMAPK1LMNARECQLCYP1B1 | |
| SCHEMBL3498434 | 0.84 | BCHE (0.63) | MAPTMAPK1LMNARECQLCYP1B1 | |
| SCHEMBL1501197 | 0.84 | CYP1B1 (0.61) | MAPTMAPK1LMNAHPGDNPC1 | |
| Ethyne SCHEMBL27085492 | 0.83 | MAPT (0.55) | MAPTMAPK1LMNAHPGDNPC1 | |
| SCHEMBL10416123 | 0.83 | MAPT (0.79) | MAPTMAPK1LMNAHPGDNPC1 | |
| SCHEMBL17459328 | 0.82 | MAPT (1.00) | MAPTMAPK1LMNAHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903288-B | Imidazaphenanthridine compound and preparation method and application thereof | 浙江大学 | 2021-02-23 | — | — | CN | disclosed |
| CN-110903288-A | Imidazaphenanthridine compound and preparation method and application thereof | 浙江大学 | 2020-03-24 | — | — | CN | disclosed |