4-Chloro-Benzoic Acid

4-Chloro-Benzoic Acid

SCHEMBL28384

O=C(O)c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 1.00
ALOX15 P16050 1/20 1.00
SRD5A2 P31213 3/20 0.85
TP53 P04637 1/20 0.71
ALDH1A1 P00352 2/20 0.65
CES2 O00748 2/20 0.65
CES1 P23141 2/20 0.65
RXRA P19793 1/20 0.60
RXRB P28702 1/20 0.60
CA1 P00915 4/20 0.59
CA2 P00918 4/20 0.59
NR4A2 P43354 1/20 0.59
CA12 O43570 1/20 0.57
CA3 P07451 1/20 0.57
TYR P14679 1/20 0.57
DRD1 P21728 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Chloro-Benzoic Acid SCHEMBL1331727 1.00 TSHR (1.00) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL32665742 0.97 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL11173042 0.97 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL30296976 0.97 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL9316886 0.97 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL2918294 0.97 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL3150134 0.97 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL8024007 0.97 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL9493329 0.97 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL7634885 0.97 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13963 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903866-B Polyvinyl alcohol modified multifunctional powder slump retaining agent and preparation method thereof JIANGSU ARIT NEW MATERIALS CO.,LTD. (CN) 2026-05-26 CN claimed
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
US-20250243137-A1 METHOD FOR PREPARING 3-CHLOROBICYCLO[3.2.1]-3-OCTEN-2-OL SHANDONG WEIFANG RAINBOW CHEMICAL CO.,LTD (CN) 2025-07-31 US claimed
EP-4293072-B1 MECHANOCHEMICAL PROCESS FOR THE PRODUCTION VALUABLES FREE OF PERSISTENT ORGANIC POLLUTANTS AND OTHER ORGANOHALOGEN COMPOUNDS FROM WASTE OF PLASTICS AND PLASTIC LAMINATES SMART MAT PRINTING B V (NL) 2025-07-23 EP claimed
CN-115873270-B Cell-mediated degradation independently controllable gelatin-multi-arm polyethylene glycol hydrogel system and preparation method thereof 西安交通大学 2025-06-17 CN claimed
CN-120136947-A 4-Androstenedione derivative and preparation method and application thereof 华东师范大学 2025-06-13 CN claimed
CN-120137643-A Composite material, preparation method thereof, photoelectric device and display device 广东聚华新型显示研究院 2025-06-13 CN claimed
US-4162363-A BY REACTION WITH OXYGEN AND A CARBOXYLIC ACID COMPONENT PHILLIPS PETROLEUM COMPANY (US) 1979-07-24 US claimed
US-4152160-A PHOTOTHERMOGRAPHY, SILVER BEHENATE FUJI PHOTO FILM CO., LTD. (JP) 1979-05-01 US claimed
US-4095037-A BISMUTH COMPOUNDS, ALKALI METAL COMPOUNDS, NITRATES PHILLIPS PETROLEUM COMPANY (US) 1978-06-13 US claimed
US-4093638-A Simultaneous preparation of organic acid chlorides and trichloroacryloyl chloride and product PRODUITS CHIMIQUES PECHINEY-SAINT-GOBAIN (FR) 1978-06-06 US claimed
US-4086423-A CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND MERCK & CO., INC. (US) 1978-04-25 US claimed
US-4076717-A Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid G. D. SEARLE & CO. (US) 1978-02-28 US claimed
US-4044041-A CARBOXYLIC ACID WITH CONJUGATED DIENE PHILLIPS PETROLEUM COMPANY (US) 1977-08-23 US claimed
US-RE29226-E Preparation of carboxylate and sulfonate salts of 1-cis-(3-chloro-2-propenyl)-3,5,7-triaza-1-azoniatricyclo(3.3.1.13,7)decane-II THE DOW CHEMICAL COMPANY (US) 1977-05-17 US claimed
US-4007168-A Process for preparing penicillins derivatives PALOMO COLL A L 1977-02-08 US claimed
US-3956168-A QUATERNARY AMMONIUM COMPOUND DAINIPPON INK AND CHEMICALS, INCORPORATED (JA) 1976-05-11 US claimed