4-Chloro-Benzoic Acid

4-Chloro-Benzoic Acid

SCHEMBL8024007

O=C(O)c1ccc(Cl)cc1.[NaH]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.94
ALOX15 P16050 1/20 0.94
SRD5A2 P31213 3/20 0.81
TP53 P04637 1/20 0.67
ALDH1A1 P00352 2/20 0.63
CES2 O00748 2/20 0.62
CES1 P23141 2/20 0.62
RXRA P19793 1/20 0.58
RXRB P28702 1/20 0.58
NR4A2 P43354 1/20 0.57
CA1 P00915 4/20 0.56
CA2 P00918 4/20 0.56
CA12 O43570 1/20 0.55
CA3 P07451 1/20 0.55
TYR P14679 1/20 0.55
DRD1 P21728 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Chloro-Benzoic Acid SCHEMBL28384 0.97 TSHR (1.00) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL1331727 0.97 TSHR (1.00) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL32665742 0.94 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL9120766 0.94 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL30296976 0.94 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL7634885 0.94 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL3150134 0.94 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL2918294 0.94 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL9493329 0.94 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1
4-Chloro-Benzoic Acid SCHEMBL9316886 0.94 TSHR (0.94) TSHRALOX15SRD5A2TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243137-A1 METHOD FOR PREPARING 3-CHLOROBICYCLO[3.2.1]-3-OCTEN-2-OL SHANDONG WEIFANG RAINBOW CHEMICAL CO.,LTD (CN) 2025-07-31 US claimed
CN-118993875-A Method for recovering active ingredients in p-chlorobenzaldehyde wastewater 江西世龙实业股份有限公司 2024-11-22 CN claimed
WO-2024152641-A1 PREPARATION METHOD FOR 3-CHLOROBICYCLO[3.2.1]-3-OCTEN-2-OL 山东潍坊润丰化工股份有限公司 2024-07-25 WO claimed
CN-114075663-B Water-based treating agent for carbon steel surface, well corrosion-resistant carbon steel and preparation method thereof 宝山钢铁股份有限公司 2023-09-12 CN claimed
CN-115960653-A Leveling liquid additive for wet leveling of common cold roll and leveling liquid 宝山钢铁股份有限公司 2023-04-14 CN claimed
CN-112679384-B Preparation method of p-cyanobenzoic acid 国药集团化学试剂有限公司 2023-04-07 CN claimed
CN-115784837-A Preparation method of 3-chlorobicyclo [3.2.1] -3-octen-2-ol 山东潍坊润丰化工股份有限公司 2023-03-14 CN claimed
CN-115572358-A Drag reducer for fracturing fluid and preparation method and application thereof 广饶六合化工有限公司 2023-01-06 CN claimed
CN-115215738-A Preparation method of p-chlorobenzaldehyde 柳州东风容泰化工股份有限公司 2022-10-21 CN claimed
CN-114075663-A Water-based treating agent for carbon steel surface, good corrosion-resistant carbon steel and preparation method thereof 宝山钢铁股份有限公司 2022-02-22 CN claimed
CN-108793750-B Mica stone-based ceramic glaze 福建省德化新凯丰陶瓷有限公司 2021-06-01 CN claimed
CN-112679384-A Preparation method of p-cyanobenzoic acid 国药集团化学试剂有限公司 2021-04-20 CN claimed
CN-112048126-A High-compression-resistance MPP (modified polypropylene) solid-wall pipe and preparation method thereof 杭州普昌科技有限公司 2020-12-08 CN claimed
CN-111909018-A Process for extracting p-chlorobenzaldehyde and p-chlorobenzoic acid from p-chlorobenzoic acid sodium wastewater 聊城隆盛化工有限公司 2020-11-10 CN claimed
CN-111574322-A Preparation method of difluoromethyl aromatic compound 南京工业大学 2020-08-25 CN claimed
CN-110724213-A Synthesis method of antiviral active bagasse xylan cinnamic acid/m-chlorobenzoic acid diester 桂林理工大学 2020-01-24 CN claimed
CN-110713559-A Method for synthesizing active cinnamic acid/p-chlorobenzoic acid bagasse xylan diester 桂林理工大学 2020-01-21 CN claimed
US-5212261-A LATENT, HEAT-CURABLE EPOXY RESIN COMPOSITIONS CONTAINING METAL CARBOXYLATE CURING SYSTEMS HENKEL RESEARCH CORPORATION (US) 1993-05-18 US claimed
WO-1992011307-A1 LATENT, HEAT-CURABLE EPOXY RESIN COMPOSITIONS CONTAINING METAL CARBOXYLATE CURING SYSTEMS HENKEL RESEARCH CORPORATION (US) 1992-07-09 WO claimed
US-4089755-A CATIONIC QUATERNARY AMMONIUM SURFACTANT THE RICHARDSON COMPANY (US) 1978-05-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243137-A1 METHOD FOR PREPARING 3-CHLOROBICYCLO[3.2.1]-3-OCTEN-2-OL OSTC, HAO2, ODC1 TSHR 2467/4885ALOX15 370/4885SRD5A2 271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.