SCHEMBL28384010

SCHEMBL28384010

CC(C)(C)c1ccc2c3ccccc3c3ccccc3c2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.59
ALDH1A1 P00352 3/20 0.47
NPC1 O15118 1/20 0.47
PLA2G1B P04054 1/20 0.47
NFKB1 P19838 1/20 0.47
CASP3 P42574 1/20 0.47
RAB9A P51151 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ATG4B Q9Y4P1 1/20 0.47
PGR P06401 2/20 0.46
RORA P35398 1/20 0.46
RORC P51449 1/20 0.46
RORB Q92753 1/20 0.46
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL606039 0.88 KIF11 (0.49) KIF11ALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL14042339 0.88 KIF11 (0.49) KIF11ALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL3913234 0.86 KIF11 (0.47) KIF11ALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL1205626 0.85 HPRT1 (0.56) KIF11ALDH1A1PGRRORARORC
SCHEMBL11241576 0.82 KIF11 (0.52) KIF11ALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL2246981 0.82 KIF11 (0.52) KIF11ALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL18689304 0.82 ABCG2 (0.47) KIF11ALDH1A1L3MBTL1ALOX15HSD17B10
SCHEMBL23072559 0.81 KIF11 (0.46) KIF11ALDH1A1NPC1PLA2G1BNFKB1
SCHEMBL13704986 0.81 KIF11 (0.41) KIF11ALDH1A1PGRRORARORC
SCHEMBL20232390 0.81 KIF11 (0.89) KIF11ALDH1A1PGRHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417480-B Method for synthesizing triphenylene compound 浙江工业大学 2020-04-21 CN disclosed