Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | POLB | P06746 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.60 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.55 |
| ▸ | GRK6 | P43250 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.54 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2838460 | 1.00 | PTPN2 (0.66) | PTPN2PTPN1TDP1MEN1KMT2A | |
| SCHEMBL2838465 | 1.00 | PTPN2 (0.66) | PTPN2PTPN1TDP1MEN1KMT2A | |
| SCHEMBL2837903 | 0.89 | PTPN2 (0.81) | PTPN2PTPN1TDP1MEN1KMT2A | |
| SCHEMBL2837901 | 0.89 | PTPN2 (0.81) | PTPN2PTPN1TDP1MEN1KMT2A | |
| SCHEMBL2837896 | 0.89 | PTPN2 (0.81) | PTPN2PTPN1TDP1MEN1KMT2A | |
| SCHEMBL2838378 | 0.85 | TDP1 (0.87) | PTPN2PTPN1TDP1MEN1KMT2A | |
| SCHEMBL2838383 | 0.85 | TDP1 (0.87) | PTPN2PTPN1TDP1MEN1KMT2A | |
| SCHEMBL2838380 | 0.85 | TDP1 (0.87) | PTPN2PTPN1TDP1MEN1KMT2A | |
| SCHEMBL9331034 | 0.84 | KDM4E (0.60) | PTPN2PTPN1TDP1MEN1KMT2A | |
| SCHEMBL9331029 | 0.84 | KDM4E (0.60) | PTPN2PTPN1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056914-A1 | BACTERIAL HELICASE INHIBITOR COMPOUNDS AND USES THEREOF | MICROBIOTIX, INC. (US) | 2010-05-20 | — | — | WO | disclosed |