Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.87 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.60 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
| ▸ | P4HB | P07237 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2838380 | 1.00 | TDP1 (0.87) | TDP1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL2838378 | 1.00 | TDP1 (0.87) | TDP1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL15828188 | 0.93 | TDP1 (1.00) | TDP1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL5991606 | 0.88 | TDP1 (0.72) | TDP1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL2838460 | 0.85 | PTPN2 (0.66) | TDP1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL2838462 | 0.85 | PTPN2 (0.66) | TDP1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL2838465 | 0.85 | PTPN2 (0.66) | TDP1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL17762701 | 0.82 | DUSP22 (0.66) | TDP1MEN1KMT2APOLBMAPT | |
| SCHEMBL5996448 | 0.81 | HSPD1 (0.75) | TDP1MEN1KMT2APOLBMAPT | |
| SCHEMBL9331034 | 0.81 | KDM4E (0.60) | TDP1PTPN2PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056914-A1 | BACTERIAL HELICASE INHIBITOR COMPOUNDS AND USES THEREOF | MICROBIOTIX, INC. (US) | 2010-05-20 | — | — | WO | disclosed |