Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 6/20 | 0.47 |
| ▸ | STK17B | O94768 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 6/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29785350 | 1.00 | BTK (0.47) | BTKSTK17BSTK17AMERTKCKS1B | |
| SCHEMBL20674042 | 1.00 | BTK (0.47) | BTKSTK17BSTK17AMERTKCKS1B | |
| SCHEMBL4256566 | 0.87 | BTK (0.48) | BTKSTK17BSTK17AMERTKCKS1B | |
| SCHEMBL4256565 | 0.87 | BTK (0.48) | BTKSTK17BSTK17AMERTKCKS1B | |
| SCHEMBL13671985 | 0.86 | STK17B (0.45) | BTKSTK17BSTK17AMERTKCKS1B | |
| SCHEMBL4475865 | 0.86 | STK17B (0.45) | BTKSTK17BSTK17AMERTKCKS1B | |
| SCHEMBL30125365 | 0.86 | STK17B (0.45) | BTKSTK17BSTK17AMERTKCKS1B | |
| SCHEMBL25691681 | 0.86 | STK17B (0.45) | BTKSTK17BSTK17AMERTKCKS1B | |
| SCHEMBL4549835 | 0.85 | STK17B (0.43) | BTKSTK17BSTK17ACKS1BSKP1 | |
| SCHEMBL29437412 | 0.85 | STK17B (0.43) | BTKSTK17BSTK17ACKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914267-A | Pyrimidopyridone or pyridopyridone compound and application thereof | 江苏奥赛康药业有限公司 | 2020-03-24 | — | — | CN | disclosed |