Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418620 | 0.89 | TSHR (0.50) | TSHRSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL188026 | 0.82 | CA4 (0.48) | TSHRNPC1RAB9AKMT2AMAPT | |
| SCHEMBL31036946 | 0.76 | TSHR (0.50) | TSHRSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL10913475 | 0.76 | TSHR (0.50) | TSHRSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL1053023 | 0.76 | TSHR (0.50) | TSHRSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL28674721 | 0.74 | SMN1; SMN2 (0.38) | TSHRSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL1039749 | 0.73 | TSHR (0.52) | TSHRSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL1482112 | 0.73 | CA4 (0.43) | TSHRNPC1RAB9AKMT2AMAPT | |
| SCHEMBL10570950 | 0.72 | CA4 (0.48) | TSHRSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL1608968 | 0.72 | CA4 (0.48) | TSHRSMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406540-B | Procatalyst for polymerization of olefins | SABIC环球技术有限责任公司 | 2020-04-17 | — | — | CN | disclosed |